Wernicke-Korsakoff’s syndrome

It is a neurological disorder where Wernicke’s encephalopathy and Korsakoff’s psychosis are acute and chronic phases respectively of the same disease.

Also known as cerebral beri beri is profoundly seen among chronic alcoholics. This is mainly because alcohol in the body reduces the thiamine (vitamin B1) absorption from the gastrointestinal tract and also conversion of thiamine to thiamine pyrophosphate (active form of thiamine).

It’s characterized by global confusion, opthalmoplegia, cerebral ataxia, memory loss, psychosis, retrograde and anterograde amnesia etc.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s